Protein Details: TWiK family of potassium channels protein 12

Protein ID

ICDB_Pro_0856

Protein Name

TWiK family of potassium channels protein 12

Gene Name

twk-12; F29F11.4

Organism

Caenorhabditis elegans

Length

713 amino acids

AlphaFoldDB

AF-Q19907-F1-model_v4.pdb

Function

Sequence

MTLFKKIQWFCNLIRLRSYYKFLLLIAYTAFGAWLFRTYELQADIKRRSVFGNTTNLVRRQLAERWIEMHKDAVLRNDSALRFRRAAEAVEWLLDELNLSDHIRDLSEETPWTWTGAMFYAGQLYTTIGYGYPTTKTDEGRICTIFYALFGIPCFLMYLKIENAIEWKKDKQLGKRALKMHGLINDSFQSIGKTLSKKMKKYYKKLRRSRVGRILLPTRVTAMKDGFEDPEAAEERKKKPFPIPIAIIMLIIWICFSASMFCIWEDTWVFSSAVYFFIVSISTVGLGDMLFRTPDMMVFNFLLILVGLALLSMCFELITDRVAKWKQKRFDEHIKKVQKMAFQVFEKDPFIEEAPPLGIRMAPNLMQIAATHVSEEKRGFFAEFKDWFAGKVTDNVIQSKLEDSDDESDSEEALEEFDSPQIATVTANDLIVCSNGAATRRVSKQSYALSDISNLSNSKILPGNNYGQLLDRIKAMEKFKPKKNDLDSRMFAKFLENKKLAKILEQTELRELATVSCQTDLSGLVVQRRNPKGRHARIGSCSSQSTMSTLLPNKMHAPDEDSVMSFTFGDLKFDYKTEPFIDEYYIRESNHSIFDFDEDETVRIPQKMLISRPGMPPPPPSRPLNLASPLRTLLEKEQKYDEDPEIQLTPRRLNSLSDIQARKVKLGVDENLQHARLVCGLLPQDFDSPSTSTSTSMIDSGYELSKRDASTMA

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1126/science.282.5396.2012; 10.1074/mcp.m600392-mcp200

RefSeq

NP_505731.3